Given its unique optical properties (maximum absorbency, light and information storage etc.), offering a wide range of application possibilities, BACTERIORHODOPSIN is one of the most interesting modern materials. That is why it comes more and more to the center of research and development projects of many powerful research and industrial centers (viz. N.A.S.A. document, articles, clientele etc. at the end of the analysis).
Bacteriorhodopsin is an ingredient of the microorganism Halobacterium halobium, which resides in waters of the hot zones of our planet, containing large concenrations of salt.
Halobacterium halobium needs salt concentrations of at least 12 %, still it is found also in saturated salt solutions and even in salt crystals.
To survive in these extreme conditions, the bacterium has developed, in the course of its evolution, a unique system:
It converts, with high efficiency, the light energy into chemically stored energy.
The core of this system is Bacteriorhodopsin, a light sensitive membranic protein closely related to the optic rhodopsin of human eyes.
Bacteriorhodopsin is an ingredient of the so-called purple membrane, an intensely colored and clearly defined area of the cellular wall of the bacterium.
It is a protein composed of 248 amino-acids, which penetrates the membrane in the form of seven a-helical cylinders. In the center of these cylinders is found – connected to the amino-acid called lysin – the Carotinoid Tunica, as a coloring substance.
The molecules of Bacteriorhodopsin are classified as tripartite on the membrane, forming a two-dimension hexagon matrix, inside the double lipid stratum.
Under the influence of light, a photochemical cycle is initiated, during which the Bacteriorhodopsin molecule passes from many stages in a very short time. After that, the tunica is isomerized by the configuration all-trans-zur 13-cis and then a proton from the inside of the membrane is transferred to the exterior.
The resulting product is used to store, via an ATP-ase, chemical energy in ATP form.
Consequently, the purple membrane functions as a light-driven pump of protons for the organism to acquire energy.
However, the photochemical system of Bacteriorhodopsin shows additional properties, making it avery interesting molecule for industrial applications:
Halobacterium halobium can be produced without notable difficulties and in commercial level by fermentation, if the appropriate know-how exists,. After having destroyed cells by decreasing the salt content, the purple membrane is obtained by partition, in a high purity condition.
The photochemical activity of Bacteriorhodopsin as a protons source continues to exist even after isolating the purple membrane from the cellular fragments and under appropriate conditions, even after delipidization, is still stable for more than one year.
The resistance against ions radiation is remarkably high.
As a consequence of the wide absorption spectrum of Bacteriorhodopsin in wild condition, the photo-cycle can be practically be initiated via the whole spectrum of visible light. Thereafter, in a very short time, the relatively long living intermediate M condition is obtained, from which the molecule comes back automatically to the substantial condition, under violet light radiation. Thus Bacteriorhodopsin acts as a reversible optical storage agent, being able to switch conditions in a very short time, under light radiation of appropriate wave length.
Given that, within a very restricted space, a great number of Bacteriorhodopsin molecules are arranged with always-constant orientation, a high storage capacity can be obtained, during its application as an optical storage agent, theoretically up to 6-7 GB/cm2 .
Our relation with Bacteriorhodopsin
The partners of our company have produced with an exclusive method Bacteriorhodopsin of high quality. The patent of the method is secured and its number is 1004510.CERTIFICATION
Our method can give any quantity of BACTERIORHODOPSIN at very low prices so tha it can be commercially exploitable given the today's prices internationally. Based on our production cost the experimental projects with Bacteriorhodopsin as a main component could become commercially exploitable [memories, holographic films, cd's, biosensors, etc].
Uses of Bacteriorhodopsin:
- General Medicine
- Bio-computers and bio-TV-sets
- Photoelectrical cells and photochromic materials
- Storage devices
- Production of inks preventing counterfeit
- Development activator for bio-objects / microorganisms and animals
- Microorganisms activator used in biotechnology
We are seeking collaboration in the following fields:
a]Researching for the production of model products based on BACTERIORHODOPSIN.
b] Commercial-Investing .
We are seeking collaboration with Investors for the upgrading of our laboratories and the creation of a complete BACTERIORHODOPSIN laboratory in order to develop an international sales network with a continuing research for new products at the same time. [There is a full and complete plan]
WE ARE OFFERING OUR PARTNERS
B1]Production know-how with production contracts for any quantity and low price in case of commercial application.
Β2]The necessary human resources for the management of the laboratories and the production.
B3]The necessary quantities for the cases of our research collaborations.